Poor Response to IVF Drugs??? Need Advice!
58 Replies
Blakey - July 5

Hi guys!
Trying...that is great news that your having your ER tomorrow..whewhoo!! I am so excited for you! see, you didn't give up, and those follies continued to grow for you. Here's hoping that one (or maybe even 2) of those follies holds the perfect golden egg for you!! I m so excited for you- and Christina you'll be next! Wishing you both truckloads of baby dust wishes...

Trying, I go in tomorrow for more blood work so my RE can see where i am in my cycle. I pray I don't have an obstruction, but my body is telling me I might. @ ruptured cysts in the months of May and June, right when AF was due..just to suspicious. I guess time will tell. If I do get AF it will be next weekend, or again, I could be getting another rupture. its as my RE pointed out..she thinks I am definitely ovulating (the past 2 months since my procedure) she thinks theirs an obstruction because my lining wants to shed, but it can't something is stopping it, and that's when I get the pain, of the cyst. I am nervous but tryoing not to think about too much, and know my RE is monitoring. I guess time will tell. Yes, I am thinking that I will most likely have to have a hysterscopy to ck for scar tissue. Just praying I won't need another lap0- but will if theirs scar tissue. All of these obstacles..and Its out of my control...(big sighs) trying to remain positive. Good luck!! :o)

 

Karri - July 6

Question for anyone who has some advice. My husband and I have been trying to get pregnant for almost 2 years now. After one year we went to the OB and he sent us to an infertility Dr. My husband was tested and he is fine. Me on the other hand I seem to go down hill fast. I just dont know how much of this I can take and I have really barely started on this crazy path of infertility. Last November I had an HSG and they found the my right tube was blocked so they unblocked it and put me on Clomid and sent us home to try. I have been on Clomid for 8 months now and nothing. In June the Dr brought me in to do Vaginal Ultrasounds around the time when I should ovulate. So starting at day 10 I would do an ultrasound every day or everyother day depending on what they would see. My follicles always start out looking good and then when it gets close to day 14 it's like they shrink. In fact this month (July) I went in on day 10 and I had two that measured at 14 each and the Dr was talking to me about the possiblity of multiples and then on day 12 I went back and I only had one follicle and it measured an 8. He said it was not a good cycle and to not try IUI this month. Understandable but so disappointing! So now I have been diagnosed with PCOS and he decided to prescribe me a different medication. I'm on Metformin now. One a day for the first week and then up to the normal dose of 2 a day. Has any one else out there been on this particular medication? He is planning on using it in conjunction with femera but wants me to wait one month for my body to get used to this new medication. So looks like August is out of the question for us too. Both these medications scare me. It's like the further along you go the crazier things get. Advise to keep me sane?

 

trying4pg - July 8

Hi Karri! I don't know much about metformin, but I was talking to Molly on our thread (* TWW and buddies wanted ...or somethin like that). Molly knew a tonne about the drug and also has PCOS I believe...so I am sure she could help you. Blakey - I sure hope you don't have an obstruction....how was your doc appt yesterday? Any info from your blood work. If there is a problem can they rush you through your appts so that you are back on the TTC wagon again. Christina - I am wondering how this whole ordeal has gone for you? Please keep me updated. I retrieved 6 mature embies on Friday and 5 have fertilized, so my transfer is set for tomorrow afternoon.

 

Blakey - July 8

****Trying- congrats on having 5 fertilized egges...Oh my gosh, that is so awesome, you must have been thrilled with that number! :o) Today your going in for your transfer! you may be there right now as I am typing to you...ver yexcited for you hun! Heres hoping you have a fast 2ww!! keep busy, and treat yourself to things you enjoy...but most importantly take it easy, and treat yourself as you are indeed pregant! Are you taking PIO injections now? You made it through IVF....your almost there!
*****Christina- hope everything is going well with you too,,,I know you and trying were cycling at pretty much the same time..did you have your retreival? plese ck in when you can,okay! thinking of ya!
******Hi Karri- I am sorry for your frustrations and delays, with these obstacles you are facing...but hang in there. Sounds like you are in good care with your Dr. I'm sorry, I don't know anything about those meds you mentioned: Medformin, or Femera, but I have read a lot of posts, and know those meds are prescribed to a lot of women. I am sure your being monitored closely, nd you'll be able to jump back on the TTc wagon in know time. Just think of it as another step closer into your journey..it will all work out. Maybe you can call your RE, or team nurse, if your concerned about the meds. and they can help you understand them a bit better..all the best!
***as for me...thanks trying, I did hear from my RE's office on friday regarding my blood work. I did ovulate this month, and my levels are where they should be, so I should get AF next weekend, If I don't, (and get another cyst) then it is most likey I have an obstruction..and that's what scares me. I am to call their office if I don't get AF by next Monday- and then we'll take it from their. I sure hope they will be able to settle this problem for me, if it is an obstruction. I will probably have to have HSG to get a better look at my uterus, and see what's going on...my RE said if it is an obstruction it's caused from scar tissue from the d&c- it does worry me, cause I don't want to have another surgery. It is all the delays I am facing right now..that gets me so down. I had the d&c in april, from my m/c and thought by now, I would be starting IVF again. I am praying that I get AF....and that the cysts were maybe just my hormones acting wacky, and my endo acting up. Thans for your thoughts!

Hope your doing well trying...can't wait to hear you next update!! I hope your little embies will find a nice cozy spot to get comfy for the next 9 months...you might even have twins! :)

 

Christina97 - July 8

Hey girls...checking in for a moment thanking all for the good wishes! Trying - I am SO excited you got 5 - WOW!!! Sending you lots of babydust for the transfer!!! I had my retrieval yesterday and they got 20, but only 8 were mature and 3 fertilized. Feeling very down now...if they survive to Tuesday that's when my ET will be. I know it's awful for me to say this, but I hope I have a better chance next time :-( Blakey - Know that I am thinking of you as I had cysts when I took clomid and hopfully yours will pass soon so you can move to your IVF cycle!

 

Christina97 - July 8

Gosh, once again, my fingers work faster than my brian - SORRY!!! I did not get 20, rather 10 were retrieved. Ugh...I just need to get some rest, LOL!!!

 

Blakey - July 8

Chirstina- sorry for you dissapointment with your retrieval. I know their is just so much "guess work" with IVF..and we never know what's going to be...but I would still be happy with having 3 that fertilized. I hope you get a good report on their sub-dividing nicely for you...Thinking of you hun! Take care of yourself..and your transfer will be here in know time. I know you've heard this before but it is quality vs. quantity...so I am praying that the ones you end up transferring.(hopefully all 3) will be just perfect! Thiking of ya..and thanks for your thoughts! :-)

 

trying4pg - July 8

Hiya kiddos! Christina...don't you dare give up on me yet. You have 3 embies...(that will survive till Tuesday) what were you planning on transferring anyways...all 10???? As I told my doc when he mentioned my low eggs..."why would I need more if these are all gooders anyways". He laughed and said I was right. Christina - you have 3 little ones ready to go in your uterus...don't give up on them...relax...and enjoy your 2ww. By the way guys, my transfer is scheduled for tomorrow at 1:30 p.m. I am having acupuncture done before and after the transfer as well (I go for acupuncture twice a week normally). Blakey I know your frustrations...that how I felt getting to this point. I was ready to do my IVF in Feb, when they found a polyp on my uterus. I had to have surgery in April, then wait till now to get things going. It is so frustrating when you want something NOW and have to wait. I hope for you, the weird periods you have been getting are just hormone changes and you will be ready to go. Thanks for the kinds words ladies! Baby dust. I need your prayers...and you have mine!

 

Blakey - July 9

Hi trying!!! so excited for you!!! So your transfer is tomorrow...yay for you! Wishing your an awesome transfer! I always love the day of transfer, it's so exciting, and you'll get to see everything on the monitor!! they'll give you pics of your little baby embies too!! all he best to you...thanks for your encouragement. Your so right, I just want things to move along again, and it's out of my control for now. I am just praying I don't have to go through another surgery, it scares me to think about it,...but if I have to, so be it, I have to...to be able to move forward...I'm sending some major baby prayers for you...that your little embies stick stick stick!!!
Hi Christina!- you too kido, you and trying are their together...3 is awesome...so don't give up! All the best to you on Tuesday for your transfer! good luck guys...praying for yA!
Hugs...and truck oads of baby dust...sprinkle, sprinkle, sprinkle....angel wishes!!

 

trying4pg - July 10

Hiya gals...well mission complete. I am home to 3 little embies...as long as I didn't launch them out of my uterus minutes after the procedure when dh accidentally made me laugh really hard. I can't remember why and them more I tried to yell at him, the harder I laughed. Anyways, enough about me. Christina...I am hoping like crazy that you were able to transfer your little embies as well today. I would love it if you would update us. Also, are you on any meds as well. The docs gave me progesterone supplements and estrogen too I think. I feel huge and bloated and like Dolly Parton right now. I stayed in bed from the time I got to the hotel yesterday and for most of today (except when I was travelling) but I don't think I really need to. Tomorrow a.m. I am back at work, but I will take it easy for the rest of the week. Blakey...any sign of AF yet. I hope she shows up soon! If you had an obstruction, do you think it is in your tubes or your uterus. I thought a d & c scrapes your uterus...but I really don't know. I really hope that is not the case and that af will come and you can ttc again right away. It could be your body readjusting again after the m/c. By the way...I am so sorry about that ...I don't know if I mentioned that before. 12 weeks must have been absolutely devastating for you. Did you do tests after to see if they could determine a cause. I really wish you success Blakey as you have been such an encouragement to me. Talk to you soon ladies...baby dust

 

trying4pg - July 11

Christina...are you up and running yet? How did it go? How about you Blakey?

 

Blakey - July 11

Hi trying! yay for you, and your 3 embies..awesome, awesome news!! I am sending you truckloads of positive baby wishes!! i hope they all find a cozy little spot for the next 9 months! Can't wait for your beta! Will you test early? I never did, was always too afraid. Hope your taking it easy, no heavy lifting or anything. I was chuckling when you talked about how you were laughing so hard, you thought they might come out...I have done that myself..and talked to so many women who also felt the same. I remember after 1 of my transfers I asked the nurse if sneezing would effect it? lol...I couln't bleive i even asked that question, what a nut! She made me feel better when she told me she gets that question a lot! lol...anyway...take care okay! :)
Christina- hope your doing well too, just like trying! Hope you had your transfer yesterday...and are home resting. Please let us know when you can..okay. We're thinking of you!
As for me, thank you trying for your words. yes, the m/c was very hard, especially after ttc for so many yrs. but we are optimisitc it will happen again. yes, they had done the testing, and it was chromosome 21- which is pretty consisitnet with downs. So needless to say, I was very surprised. My Dr. told me, that it was most likey the heart that was weak, and that's what eneded the pregnancy. Most pregnancies with downs babies continue, and as my Dr. pointed out, I was in a situation where I didn't have to make a decion on what to do, my body made it for me. It was still very difficult, and sad. My RE said that the chances are there to happen again, becuae of my age (I am 40) so chances do go up for a woman my age. Next time I would most likley do the amnio to see for any problems. The dr. told me, my chances are also very good for a healthy pregnany next time, so that is what i am praying for. I hope to see AF this weekend. My RE told me last Fridaya fter my blood test, that I should see it within the next 7-1o days, so by the weekend- I am hoping it will show! I have waited almost 3 months. I am afraid if it doesn't show, then most likely it's a blockage./obstruction like my RE said. I m praying it's what you said, I have thought about that to, it's just my body trying to get back to normal, and my hormones were just so out of whack. I guess I will know this weekend. If no AF by Monday, I have to call my RE. I am not sure where the blockage would be...maybe in the uterus? or by the cervix? I just don't know. I even remember my OB telling me she went in by suction only, so how would I get scare tissue from that, it wasn't an instrument? I am just so upset by it, not to mention that this OB i had was a new OB, nd she was terrible. Needless to say, I have left that office, and will return to my prior OB. The only reason I had left, was because i thought I wanted a woman OB, but she was terrible. It was a bad exp from the get go.
I will keep you posted.. thank for your thoughts, means a lot!

Take care...thinking positive thoughts for you...I just have such a good feeling for you! Was this your 1st cycle of IVF? baby dust...sprinkle sprinkle.... :o)

 

Christina97 - July 12

Blakey - I have something to share with you since you have been so wonderful to me over these past 2 hard weeks. I had no idea about the downs. My BF's first pregnancy had all the markers for downs and they did the amnio and everything turned out to be ok and her son is a very healthy almost 2 year old! Her second pregnancy ended at 24 weeks as she had more definitive markers for downs with this son. They did the amnio and she would up losing him about a month ago. They didn't say it was from the amnio though so don't misunderstand my point which is her son who is almost 2. She was told that she would run the risk every pregnancy - and BTW, she is only 31. But, you can have a very healthy baby and my heart really breaks for all you have been through. I am praying that you get that healthy little bundle of joy soon :)

 

Christina97 - July 12

trying - not doing so good here. I had my transfer on Tuesday morning (2) and one arrested overnight. They were graded as "average"...that wasn't pleasant to hear and I actually broke out in tears after the procedure. My doctor rocks though - he held my hand and just listened to me and gave me the best pep talk. So, I spent Tuesday and yesterday in bed but went to work today. I just feel hopeless and I am panicked that I only have one more attempt after this and what if it fails??? I swear I get so upset that I could cry - isn't that pathetic? I just wish I could be happier and hopeful with how this all turned out, but I am not. Blakey and trying - know that I appreciate all of your support...I really do!

 

trying4pg - July 12

Oh Christina - I know just how you feel. I have been so emotional and terrified since my transfer that it has been horrible. I had a huge fight with my dh the night before last and then cried myself to sleep because I felt so guilty that I was killing my embies with all my negative energy. I am definitely TERRIFIED too because I don't know what I am going to do if this fails. I am so glad you transferred 2 embies...it only takes 1 ...right... and my doctor says it doesn't matter if they are average, bad, or SuperStar Embies...some take and some don't. You have just as much chance as anyone else to get preggers. We need to stick together and thank god we have such terrific support. Speaking of terrific support....how are you Blakey. No signs of AF yet....cramps...irritability...anything? Weird about the possible blockage thing...sometimes you wonder what goes on in our nether-regions as a part of our TTC therapy. I swear I got a polyp from one nurse that was really AGGRESSIVE with my IUI. I am sure she was poking the cathetar right into the end of my uterus and it hurt like hell. Every time I had her, I bled and was really sore and crampy for a few days. A couple months later...I have a polyp at the back of my uterus...right where I thought I was being poked. Call me paranoid, but it seems to be a bit of a coincidence. Sooo to me it would seem strange that you would have an obstruction after a laser type surgery. Good Heavens. I just had a hysteroscopy and a biopsy of my polyp in April....it wasn't too bad, but I hated the delay. (I imagine you would too) As for the chromosome 21 - that would definitely be a decision that I would not want to have to make. However, the downs babies (adults now) I know are such angels....I don't know what I would do. There is such a sweetness about them. Tough call and one I don't know how I would make. Oh well, one miracle at a time I suppose. Well...I am sending angels out to stand over you guys and shower you with baby dust and healthy babies. Talk to you soon!

 

Blakey - July 13

Hi- first, Christina, I am sorry to hear that you were feeling a bit down ofver the past couple of days, but I'd like to share some news with you too. On My successful cycle, I had 2 embies tranferred, 1 was grade C (average) 8 cell, and the other was grade B- 7 cell- and 1 of them implanted, so you can't give up hun. you have to remain positiv,e becaue the mindset, does have alot to do with it, I really beleive that, and they say that your baby picks up on that, even when they are that small...so think positive, and treat yourself as you ARE pregnant! It does only take one, and you have 2 of those little ones in there, so here's praying 1, or even the 2 stick, and get nice and cozy!! I have also heard of women who have had just 1 transferred, nd it's been a success, so it's a matter of the embryo implanting iteslf..so you can't give up. Your embies sound just fine....and they will continue to strive...so you have to keep belieivng! It sounds like you have an awesome RE who is very supportive, and encouraging, that is so important!!! Hang in there sweety, and know that dreams do and will come true! Try not to think about "the next cycle" or what if, again, you just had your transfer, you need to take care of you know for the next 2 weeks, and take it easy...no heavy lifting, etc...not even a case of soda, have DH carry that, even a gallon of water....you'll cross that bridge if you need to later on, but for now...think, and remain hopful, and positive...I am! Thank you for sharing your story regarding your friend etc...I am soory for her 2nd loss. So they told her the likelyhood of downs was there for every pregnancy? Hmmm, that surprises me because of her age, being so young. The risk is normally for women wh are 35 and older. I m happy for her she has her beautiful 2 yr. old...as I am sure she is. All the best~~ Thinking of you, and take care!
Hi Trying- hope your doing, and feeling well too!! Hope you've been taking it easy yourself..and thinking positive!!!! I have a good feeling for both of you! Thanks for you kind words also. Still no sign of AF. If it shows it will be this weekend, so I am so hoping it shows...I don't want to have to go through another surgery, and exactly what you said...all these dlays, I just hate it! I have waited so long already, and now if their is an obstruction, it adds a couple of more months now...I hope that's not the case. yes, I agree with what you said, if the OB didn't go in with a curette, to scrap, it was all done by suction, how would that cause scar tissue??? I don't get it??? It's just got to be delayed due to my hormones from the past..but now that they are on track, and my HCG is at 0, it's just got to come right??? Oh guys,....I sure hope so! I agree with what you said too, I don't know what I would do regarding a baby with downs...it so hard, and I too never want to be in that positiomn to have to decide. I do feel that god is watching over me, nd he knows what my strengths are vs. my weaknesses, and I just don't know if I would be strong enough....I pray that everything will work out for us, if we are blessed to get pregnant again. The next cycle will most likely be our last one (4th IVF)- for we have paid out of pocket the whole time. We most likley will have to take out a loan for this cycle too. I hope it will work out. If we are fortunate enough to get a BFP again, we will definitely have the amnio the next time around.
Thanks for letting me talk about it. Thank you both for you kind words.

thinking of you both...Christina, and Trying!!! hang in there U-2...and don't give up...think positive for right now your both PUPO!!!!! (PREGNANT UNTIL PROVEN OTHERWISE)
HUGS TO YOU BOTH...AND BIG BABY WISHES!!! xo :O)

 

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